Of the 1131 subjects within the randomized vehicle-clinical trials for tazarotene, 97% were white. Subjects with darker Fitzpatrick Skin Types V and VI were not studied, which results in an inadequate determination of efficacy of the product to darker skin types.  Within two trials submitted, a slight improvement in fine wrinkling was seen in 5% and 13%, respectively of both trials. All others had minimal improvement, no change or got worse.
This serum has all the usual ingredients and a few extras as well. The hyaluronic acid and retinol in this serum will act to hydrate and reduce fine lines, firming your skin – as you’ve seen in several other products on our list. But you may not know the Vitamin E will neutralize free radicals and harmful UV rays. And the plant-based glycerin will calm and hydrate the skin, making it perfect for dryness, peeling, or age spots.
The price isn't for the faint of heart, but AmorePacific Time Response Eye Renewal Creme earned splurge-worthy status with an outstanding performance in the lab, including perfect scores for firming and hydrating. Testers ranked it best for de-puffing — "It made my eyes look brighter and less puffy," said one — and appreciated its luxurious texture and mild, pleasant scent.
Another study shared information regarding use of a topical serum containing epidermal growth factor (EGF) and its ability to minimize the appearance of under-eye bags. Sixteen subjects were tested and all but two subjects reported improvement at their final visit. Improvement was quantified as 76–100 percent by two subjects, 50–75 percent by three subjects and 25–49 percent by nine subjects. Eleven subjects claimed that the bags under their eyes were definitely milder at the end of the trial compared to the first visit. Seven subjects reported greater satisfaction with their overall facial appearance.
“Although there are many factors that influence under eye bags such as genetics, allergies, medical conditions, UV radiation exposure, sleep, hydration, salt, and alcohol consumption, there is another simple factor that can influence how the skin appears around the eyes and that is how sugar can impact your skin,” says Dr. Sue Ann Wee of Schweiger Dermatology Group in NYC. The new year is a perfect time to kickstart a healthy diet and remove (or at least cut back) sugar from your diet.
Hyaluronic acid filler injections can plump up the sunken under-eye area. Fillers are priced per syringe, typically between $1,000 and $1,400, and the results can last for a year and a half or up to five years. There are also laser procedures to destroy the superficial blood vessels that are showing through the skin, though experts say tread with caution as the wrong laser can cause hyperpigmentation (or even hypopigmentation, when the area lightens too much). Treatments range between $300 and $500, and may require two or three sessions to see results, plus annual maintenance.
We almost feel as if all we need to tell you about this cream is the rating: it’s a perfect 5.0. Well, sure that happens from time to time, right? Not with 1,115 reviews at the time of this publication, though. That’s not typical at all. That’s over a thousand people giving it 5 stars, saying it’s perfect. It contains most the ingredients you’d think of for a wrinkle cream: hyaluronic acid, retinol, Vitamin E, and green tea, with the right amount of each to make all the difference. And if not, the product has a 100% money-back guarantee.
Let’s get one myth out of the way: It really doesn’t hurt that much, especially when you’re the one in control. Dermatologists use something called a Dermapen for in-office treatments, and that’s a little more intense—bleeding is a common side effect. (That’s why they call it the “vampire” facial.) But a dermaroller is a little less hardcore, and you can press as hard as your pain threshold allows.
EDITOR’S CHOICE: If you are looking for an effective, but affordable anti-aging cream, look no further than the LiftActiv Supreme. It is made by Vichy – the number 1 anti-aging brand in European pharmacies and is enriched with their signature mineral-rich volcanic water. It also contains a skin-boosting, plant-derived sugar and a powerful antioxidant to improve and promote your skin’s resilience against aging, without blocking your pores and causing breakouts. Vichy gives you the highest standards and has proven to produce long-lasting results in as little as 4 weeks! It sure sounds too good to be true, but the clinical results speak for themselves. This really is a luxurious, effective yet affordable anti-aging cream.
Anti-aging creams are predominantly moisturiser-based cosmeceutical skin care products marketed with the promise of making the consumer look younger by reducing, masking or preventing signs of skin aging. These signs are laxity (sagging), rhytids (wrinkles), and photoaging, which includes erythema (redness), dyspigmentation (brown discolorations), solar elastosis (yellowing), keratoses (abnormal growths), and poor texture.[1]

Yes, the fountain of youth is one myth that many of us wish we could prove true, but the reality is that we cannot turn back the clock. "With the aging process, the ligaments underneath your eyes that hold back fatty tissue begin to weaken, and the tissue can fall forward to form under eye bags," comments Ryan Nakamura, O.D., a VSP network doctor at Natomas Optometry in Sacramento, CA.
Skinception – Instant Wrinkle Reducer is a skincare supplement which is meant to facilitate the firmness of the skin. Its formula works to assist the skin in its hydration, making the skin more firm and increase its elasticity. The manufacturer indicates that Skinception – Instant Wrinkle Reducer is made with the blend of natural ingredients which assists the supplement meets its desired results. The expected results of the product are visible and actual youthful firmness on the user’s appearance. Check out some more wrinkle reducer, for example, Wunderlift 60-Second Wrinkle Reducer Review which might be able to reduce the wrinkles.
This serum focuses on the retinol contained within, because that is the ingredient that will stimulate the collagen production and therefore tighten your skin. But the other ingredients included in this serum will have an equally noticeable effect. The hyaluronic acid will hydrate your skin for an incredible length of time and that will leave you seeing smoothed out wrinkles and plumped skin. The aloe vera and Vitamin E will protect your skin from harmful UV rays and provide antioxidants to fight off free radical damage.
Worst experience ever. It has now been a month and a half and I still have not received my box. I have made numerous phone calls to customer service and each time they were curt and rude. I finally got a tracking number after different reps kept telling me different stories. The tracking information said it would be updated within 42 to 48 hours. Going on 96 hours tracking information has still not updated so I called customer service. The gentleman that picked up the phone treated me like I was an imbecile.
“When it comes to combating wrinkles, I always recommend incorporating retinol into your skin care routine. This is an excellent way to add the effective ingredient to your daily regimen without breaking the bank. The silky formula is proven to diminish the look of fine line lines and wrinkles and it is even suitable to use under makeup,” said celebrity makeup artist Erin Guth.

“Although there are many factors that influence under eye bags such as genetics, allergies, medical conditions, UV radiation exposure, sleep, hydration, salt, and alcohol consumption, there is another simple factor that can influence how the skin appears around the eyes and that is how sugar can impact your skin,” says Dr. Sue Ann Wee of Schweiger Dermatology Group in NYC. The new year is a perfect time to kickstart a healthy diet and remove (or at least cut back) sugar from your diet.


This innovative formula targets Collagen I and Collagen III (otherwise known as the “Youth Collagen”) to bring back your skin’s natural elasticity and firmness. Specifically designed to combat the depth, length, and width of wrinkles, this Collagex-CE formula drastically reduces the appearance of aging, targeting collagen to improve your skin’s texture and strengthen your skin’s barrier.
“There are many reasons people develop under-eye bags,” says Rachel Nazarian, M.D., of Schweiger Dermatology Group in New York City. “Oftentimes it’s a temporary swelling caused by poor lymphatic circulation or dietary factors (like high-sodium), which draws water into your skin's tissue, causing puffiness. However, there are also genetic factors that can cause your skin to weaken, which worsens with age, she adds.
Testers rated Estée Lauder Perfectionist [CP+R] Wrinkle Lifting/Firming Serum best for minimizing fine lines and wrinkles. Said one, "I had a very deep wrinkle between my eyes, and it's really starting to go away." Lab tests didn't show stellar wrinkle reduction with any of the serums, but the Estée Lauder proved itself a top-notch skin smoother. Echoed a panelist, "My face feels smoother, and my skin tone looks brighter. I have been wearing less blush!" If you want to spend smarter, go for the large size of our winners (the 3.3-oz. Lancôme, $150; the 3.4-oz. Estée Lauder, $160) and you'll slash the price per ounce by $44 and $18, respectively.
Reviews.com has an advertising relationship with some of the offers included on this page. However, the rankings and listings of our reviews, tools and all other content are based on objective analysis. For more information, please check out our full Advertiser Disclosure. Reviews.com strives to keep its information accurate and up to date. The information in our reviews could be different from what you find when visiting a financial institution, service provider or a specific product’s website. All products are presented without warranty.
As is the case with most of the body’s natural processes, collagen production naturally slows down a bit as we age. When collagen levels drop, the elasticity of our skin (and the other parts of our bodies that depend on this vital protein) soften and become more fragile. Decreased collagen levels can lead to everything from wrinkles and fine lines to increased bone fragility and de-pigmented hair color (that’s where those stubborn grays and, if we let them, eventual white hairs come from!).
The term "beauty sleep" gets thrown around all the time, but, turns out, it's a very real thing. While you sleep, your skin kicks into high gear, undergoing a long list of natural processes to help it repair and regenerate. Plus, "while you sleep, cortisol is at its lowest and anti­-inflammatory molecules like beta­ endorphins and growth hormones are at their highest, so that's when skin heals," says Amy Wechsler, M.D., a psych-derm in New York City. As a reminder, low levels of cortisol (the stress hormone) are a very good thing for your skin, since the hormone does everything from increase inflammation to up the likelihood of breakouts. So pull a few all-nighters or super-early mornings in a row, and you'll quickly see this lack of sleep show up on your face.

Using this method, you can work out that higher SPF ratings don’t actually give you much more protection than medium SPF ratings. The Skin Cancer Foundation reports that SPF 15 blocks 93% of UVB rays, SPF 30 blocks 97% and SPF 50 blocks 98%. While these differences seem insignificant, they can still make a great difference over time, especially if you have fair skin or a history of cancer.
Over the course of 12 hours I have gotten 3 conflicting emails from Allure regarding my January box. First I was told they cancelled my box and refunded my money, then they told me they are running behind and i will get in next week, then i get an oopsie we sent you wrong information i have been charged and they will send out a tracking number next week.
Genetics do play a big role. If you’ve “always” had them or since a young age, you have probably inherited them. But other factors such as lack of sleep and lack of hydration will make them worse. Also, if you don’t wear sunglasses, your dark circles may actually be hyperpigmentation. Finally, as you age, the decrease in collagen under your thin skin will make the blood vessels more visible–hence making this area look darker.
Verlayze is a premiere dark eye circle cream on the market. While other products try to approach every aspect of skin health, Veralyze was designed with specific ingredients to target dark circles beneath the eyes. This specificity means that Veralyze can pack more focused ingredients into its blend! The best part, Veralyze costs less than $30! In fact, you’re GUARANTEED results with a leading 100% Money Back Guarantee. Read more...
I signed up for the first month promotion for $7.50. They charge my card and 1.5 weeks later, they charged my card again for the next month subscription even though I haven't received the first box yet. I emailed them to cancel, they replied me with some promotion "4 boxes for $10", I refused but they ignored my answer. I kept emailing them to cancel but never got an answer from them. The next thing I know is that they already shipped another box. This is outrageous.
Protect your skin from the sun. Exposure to UV light speeds up the natural aging process of your skin, causing wrinkles and rough, blotchy skin. In fact, sun exposure is the No. 1 reason for signs of aging in the skin, including uneven pigmentation. Protect your skin — and prevent future wrinkles — by limiting the time you spend in the sun and always wearing protective clothing and a hat. Also, use sunscreen on exposed skin year-round when outdoors.
It’s tough to be consistent when you won’t see results for weeks, months, or sometimes even years. But keep the faith. A wrinkle cream with the right ingredients will ultimately keep you looking younger. “These products won’t work if you don’t use them consistently for several weeks,” says Dr. Ford. “Try taking a selfie at the beginning of treatment and again at 90 days,” she recommends. “See if change is occurring: your freckles should be lighter, wrinkles should be less noticeable, and your skin more radiant.”
If you’re looking for a more permanent solution for under eye bags caused by ageing, fillers can sometimes be a good option. This long-lasting treatment can keep eyes bag free for up to 12 months. The injections work to improve the appearance of the under-eye area by smoothing the contours of the eye socket to make it appear more youthful. Although a highly efficient and long-lasting treatment, fillers can be quite expensive and occasionally have adverse side effects, so do your research first!
Women’s Health Editor’s Note: Dr. Frey is one of my favorite contributors. Her unrelenting passion to bring patients and consumers the most factual information is completely refreshing. Dr. Frey makes the fact-based claim that “anti-wrinkle” creams do not work using evidence that comes directly from the manufacturers’ package inserts!  ….Anna Villarreal
Copper is another one of the elements which can promote the skin’s natural production of collagen. It is, in fact, a key component in the production of collagen. Copper binds to trace elements called peptides, which are compounds of amino acids that can eventually join to become a protein, and therefore becomes a copper-peptide molecule. Some copper peptides have the ability to heal wounds and build new cells, and can stimulate the production of collagen. The copper peptides transport around your body, bringing the peptides to where they are needed to nourish and restore your skin.

Even though its damage-blocking superpowers sound great, vitamin C can’t replace SPF, so be sure to wear a sunscreen along with this moisturizer during the day. This specific cream is loaded with extra skin-saving ingredients like aloe vera, two forms of vitamin B, and CoQ10. Store this bottle in a cool place and away from direct sunlight, which may weaken ingredients.

This wrinkle cream’s primary ingredient difference is the probiotic formula it contains. Probiotics can have a drastic impact on your body, both inside and out. Not only can it rejuvenate sagging skin and smooth wrinkles, it could even treat dermatological problems like acne, rosacea, and eczema. And it also includes other ultra-hydrating ingredients: aloe, jojoba oil, and cocoa butter to name a few.
THIS TOOL DOES NOT PROVIDE MEDICAL ADVICE. It is intended for general informational purposes only and does not address individual circumstances. It is not a substitute for professional medical advice, diagnosis or treatment and should not be relied on to make decisions about your health. Never ignore professional medical advice in seeking treatment because of something you have read on the WebMD Site. If you think you may have a medical emergency, immediately call your doctor or dial 911.
We’ve talked a lot about warding off wrinkles with creams, but what if you’ve taken a more drastic approach. Look, we aren’t here to judge. For many people, plastic surgery and cosmetics procedures are the perfect way to fight the signs of aging in a fast and sure-fire way. If you have recently undergone a cosmetic procedure, then you know just how important it is to find topical products that are safe to use on your skin post-procedure.
The company submitted data to the FDA from five clinical trials, which revealed moderate improvement in fine wrinkling in only 29 of 279 participants who applied tretinoin and sunscreen (compared with 3% in the control group, which used comprehensive sun protection only). Of those that used sun protection and tretinoin, 76% saw minimal improvement, no change or even worsened (compared to 88% of the control group).  All individuals within these five clinical trials had lighter skin types (Fitzpatrick Skin Types I – III.) A single study of 107 darkly pigmented subjects (Fitzpatrick Skin Types IV-VI) performed even worse. Of subjects who only used comprehensive sun protection, 49% demonstrated minimal or mild improvement in fine facial wrinkling. When compared to subjects who applied tretinoin and sunscreen only 29% showed improvement;

I agree completely. I’m pretty bent about waiting this long particularly when they took my money way earlier than ever before! 99% of the time it’s always on the 9th regardless of the day of the week in the entire almost 2 years I’ve been a loyal subscriber. This month, I was charged on the 4th. What they should have done is send out emails the day they realized the nail polish was going to be late, send the boxes the way they were and then ship the nail polish separately or in next month’s box. Their supplier issue isn’t my fault nor is it my fault that they advertised the living daylights out of this box and now can’t keep up. I do believe they are lying. If my neighbor who is a new subscriber, (this is her 1st month), got both of her boxes, where is mine? She got both on the same day, Amazon did not have the polish but the through allure did? 🤔 New customers got there’s and so did MSA but not their long time, loyal customers? Bad way to handle it

×